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Understanding Post-Traumatic Stress Disorder (PTSD): A primer

David George

Updated: Dec 17, 2024

Post-traumatic stress disorder (PTSD) is a mental health condition that arises after experiencing or witnessing a traumatic event. This condition is characterized by intense and persistent emotional and psychological distress that disrupts daily life. Although it is commonly associated with combat veterans, PTSD affects people from all walks of life and can result from a wide range of traumatic experiences.

New treatments for PTSD including combining psychological and brain-based (neurorehabilitative) therapies.  This includes stellate ganglion block and ketamine therapy.
PTSD is widely recognized as a potentially devastating mental health condition, which is a limiting perspective that limits its treatment to psychologically-based therapies. A view of PTSD as a brain-based condition is widening it treatment possibilities to a wider range of cutting-edge therapies.

Symptoms of PTSD

PTSD manifests through a combination of symptoms categorized into three main groups: Re-experiencing Symptoms, Avoidance and Numbing Symptoms, and Arousal Symptoms. Understanding these categories is key to recognizing the disorder and seeking appropriate treatment.

Re-experiencing Symptoms

Re-experiencing symptoms involve reliving the traumatic event through intrusive memories, flashbacks, or nightmares. These episodes can be triggered by reminders of the event, such as specific sounds, smells, or places. For example, a survivor of a motor vehicle accident might vividly recall the crash upon hearing screeching tires. Such symptoms often leave individuals feeling as if they are back in the traumatic moment, causing significant distress.

Avoidance and Numbing Symptoms

People with PTSD may try to avoid thoughts, feelings, or situations associated with the traumatic event. This can lead to emotional numbing, where individuals feel detached or estranged from others. Common behaviors include avoiding conversations about the trauma, steering clear of specific locations, or withdrawing from social activities. Over time, these avoidance behaviors can contribute to feelings of isolation and exacerbate depression.

Arousal Symptoms

Arousal symptoms are marked by heightened physiological and emotional reactivity. Individuals may experience difficulty sleeping, irritability, hypervigilance, or an exaggerated startle response. This state of constant alertness can lead to physical exhaustion and strain on personal relationships.

Common Causes of PTSD

PTSD can arise from a variety of traumatic experiences, including:

  • Motor Vehicle Accidents: Survivors of severe car accidents often face lingering fears related to driving or traveling in vehicles.

  • Combat: Military veterans exposed to life-threatening situations or the horrors of war frequently develop PTSD.

  • Sexual Assault: Survivors of sexual violence may struggle with intrusive memories and trust issues.

  • Natural Disasters: Experiencing events such as hurricanes, earthquakes, or wildfires can trigger PTSD.

  • Other Traumatic Events: Physical assault, witnessing violent crimes, or surviving life-threatening illnesses can also be triggers.

Duration and Impact of PTSD Symptoms

PTSD symptoms can persist for years or even a lifetime if untreated. The condition significantly affects both mental and physical health. Mentally, individuals may develop co-occurring disorders such as depression, anxiety, or substance use disorders. Physically, PTSD is associated with increased risks for cardiovascular disease, chronic pain, and immune dysfunction. These effects underscore the importance of early intervention and comprehensive treatment.

Aggravating Factors: Brain Conditions and Illness

Other brain conditions, such as long COVID, concussion, and chronic illnesses, can exacerbate PTSD symptoms. For instance:


  • Long COVID: Persistent brain fog, fatigue, and mood disturbances can intensify PTSD-related cognitive and emotional challenges.

  • Concussions: Traumatic brain injuries (TBIs) often co-occur with PTSD, complicating recovery and amplifying symptoms like irritability and memory loss.

  • Chronic Illness: The physical and emotional toll of ongoing health challenges can heighten feelings of vulnerability and distress, reinforcing PTSD symptoms.

Treatment Options for PTSD

Modern approaches to PTSD treatment emphasize both psychological and neurological interventions. Neuregen, an integrative psychiatry and neurologic health center in Scottsdale, AZ, offers comprehensive care for PTSD. Led by Dr. David George, Neuregen specializes in addressing both the psychological and brain injury components of PTSD. Their treatments include:

SGB is an innovative treatment involving the injection of a local anesthetic into the stellate ganglion, a nerve cluster in the neck. This procedure has shown promise in reducing the heightened fight-or-flight response characteristic of PTSD, offering rapid relief from symptoms such as hypervigilance and anxiety.


Ketamine Therapy for PTSD Ketamine therapy has emerged as a promising treatment for post-traumatic stress disorder (PTSD), offering rapid symptom relief compared to traditional approaches. Unlike conventional antidepressants, ketamine acts on the brain's glutamate system, promoting neuroplasticity and enhancing the brain's ability to rewire itself. Studies suggest that ketamine can reduce symptoms such as intrusive thoughts, hyperarousal, and depression within hours or days of administration. This makes it particularly valuable for individuals who have not responded to standard treatments. While its long-term efficacy and safety require further investigation, ketamine therapy represents a significant advancement in PTSD management, offering hope for improved quality of life. Trauma Psychotherapy

Evidence-based therapies such as cognitive-behavioral therapy (CBT) and eye movement desensitization and reprocessing (EMDR) help individuals process traumatic memories and develop healthier coping mechanisms.

Integrative Psychiatry

Neuregen combines traditional psychiatric treatments with holistic approaches, including nutritional support, mindfulness practices, and lifestyle modifications to enhance overall well-being.

Brain-Based Therapies

These therapies focus on restoring brain health through neurorehabilitation, and other techniques designed to regulate brain activity and improve resilience.

About the Author

Dr. David George leads an integrative psychiatry and neurologic health practice, specializing in brain injury conditions. At Neuregen in Scottsdale, AZ, specializing in cutting-edge treatment for PTSD like stellate ganglion block, ketamine therapy, and other brain-related conditions. By addressing both the psychological and neurological aspects of trauma, Dr. George and his team provide compassionate, comprehensive care tailored to each patient’s needs. Learn more at www.neuregen.com.

References

  1. American Psychiatric Association. (2022). Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR).

  2. Yehuda, R., & LeDoux, J. (2007). "Response Variation Following Trauma: A Translational Neuroscience Approach to Understanding PTSD." Neuron, 56(1), 19–32.

  3. Lipov, E., et al. (2012). "Stellate Ganglion Block Reduces Symptoms of Post-Traumatic Stress Disorder: Preliminary Findings." Pain Practice, 12(4), 289–295.

  4. Shively, S. B., et al. (2016). "Chronic Traumatic Encephalopathy and PTSD: Similarities and Differences." Frontiers in Neurology, 7, 19.

  5. Taubman-Ben-Ari, O., & Nuttman-Shwartz, O. (2019). "Post-Traumatic Stress Disorder in Motor Vehicle Accident Survivors: Prevalence and Risk Factors." Journal of Traumatic Stress, 32(2), 161–171.

  6. World Health Organization. (2018). "Preventing Mental Health Disorders After Trauma." WHO Mental Health Evidence Review.

By understanding PTSD and the comprehensive treatment options available, individuals can take steps toward recovery and reclaim their lives.

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