Start with what life feels like now
What if an illness has passed but daily life has not returned?
We help people with symptoms that linger after illness by examining the systems affecting recovery so that they can work toward daily activity at a manageable pace.
How we look at the whole picture
The infection has passed, but you still cannot get through a normal day the way you used to.
A better morning can be followed by a setback after an errand or activity that once felt easy.
You do not need to know which treatment to ask for. Start with what has changed and what you want to be able to do again.
In their own words
We understand your experience of Long COVID & Post-Viral Recovery
People often describe it in their own words long before anyone gives it a name. If one of these sounds like you, you are in the right place.
“I haven’t been the same since COVID.”
“My brain fog, fatigue, and dizziness have persisted for months after the infection.”
“I was cleared by my doctor but still can’t function the way I could before.”
“Every specialist treats one piece — nobody addresses the whole picture.”
Illustrative experiences, in the words people commonly use. The portraits are AI-generated and do not show patients.
The 7 Domains of Recovery™
Your symptoms may belong in the same conversation.
Energy, autonomic responses, cognition, sleep and immune concerns may overlap after an illness. The seven domains give us a way to assess the whole pattern.
Neuregen's proprietary 7 Domains of Recovery framework organizes that conversation around seven connected parts of your life and health. We consider all seven, then focus the evaluation on the questions your history raises.
Explore our clinical framework- 1Brain function & neural networks
What has changed in your memory, concentration, balance or sensory tolerance?
- 2Autonomic & nervous system regulation
What happens when you stand, move, rest or encounter stress?
- 3Immune function & neuroinflammation
What immune history, reactions or symptoms need a closer look?
- 4Brain energy & metabolic health
What affects your energy through the day and after activity?
- 5Structure, stability & body-to-brain signals
How do pain, posture, movement and stability affect what you can do?
- 6Psychological flexibility & behavioral recovery
How are mood, stress and patterns of coping affecting your day?
- 7Life, relationships & environment
What demands, relationships and support shape your recovery?
A plan starts with the things you want to do again.
We ask what activity feels like during and afterward, review prior evaluations, and establish a baseline. Your tolerance and response help set the pace of the plan.
01
Tell us what you want your life to look like
We start with what has changed, what you have tried, and the activities you most want to return to.
02
Answer the questions the history leaves open
We review prior reports and select relevant assessments. You should understand what each assessment is meant to clarify.
03
Agree on the priorities and the first steps
We discuss the findings, possible approaches, costs and practical constraints. The plan sets an order that fits your situation.
04
Check what changes and adjust together
We compare your response with the starting point, including daily function. If something is not helping, we discuss what needs to change.
Only then do we discuss which therapies, if any, belong in your plan. The choice depends on the findings, the evidence, your preferences and how you respond.
Talk through your situationRecovery Pathway
Long COVID & Post-Viral Recovery
Recovering what a post-viral illness took from your brain and nervous system
Conceptual artwork for the care discussion. Individual findings and treatment options require clinical evaluation.
What is happening in your nervous system
Post-viral illness — including Long COVID — creates overlapping disruptions across multiple domains. Persistent neuroinflammation (Domain 3) may be driving brain fog, cognitive dysfunction, and sickness behavior. Autonomic dysregulation (Domain 2) contributes to orthostatic intolerance, palpitations, and exertional intolerance that overlap with POTS. Neural network function (Domain 1) is impaired when neuroinflammation reduces cerebral blood flow and connectivity. Brain energy and mitochondrial function (Domain 4) are often compromised, contributing to the profound fatigue that characterizes post-viral presentations. These domains interact: immune activation suppresses autonomic regulation; autonomic dysfunction reduces oxygen delivery to already-compromised brain circuits.
Domains most involved:
Every plan starts from the same map: the 7 Domains of Recovery.
How it fits your plan
We evaluate all four primary domains and identify the pattern specific to your presentation — whether neuroinflammatory, autonomic, metabolic, or a combination. We sequence interventions starting with the most established: autonomic rehabilitation, supportive nutritional and metabolic care, graded return to activity with appropriate pacing. More advanced tools — SGB for autonomic presentations, blood rehabilitation for immune/inflammatory presentations — are introduced when the clinical picture and evidence support them. We default to the simplest, lowest-risk intervention that can move a domain forward — and escalate to more advanced or interventional care only when the evidence and the patient’s course support it.
We review your history, explain the findings, agree on next steps and check how you respond.
Potential Therapies
We use established medicine where it works, and emerging medicine where it makes sense.
These are options to discuss after evaluation, not a predetermined treatment plan. Each label refers to the condition or indication described beside that therapy; evidence can differ for another use. An evidence label does not mean FDA approval.
- Autonomic RehabilitationEvidence: Established
Core intervention for Domain 2 post-viral autonomic presentations.
- NeurorehabilitationEvidence: Established
Addressing Domain 1 neural network recovery.
- Nutritional & Metabolic SupportEvidence: Established
Supporting Domain 4 brain energy and mitochondrial function.
- Stellate Ganglion Block (SGB)Evidence: Preliminary
For the autonomic-dominant post-viral presentation.
- Therapeutic Plasma Exchange (TPE)Evidence: Emerging
For post-viral neuroinflammatory presentations; AMA-cited in guide Part 5.
- EBOOEvidence: Investigational
Metabolic and neuroinflammatory support; investigational adjunct.
Where the evidence stands
Evidence varies by therapy and by condition. Each therapy on this page carries its own evidence label for this condition, from established to investigational.
Sources and what they support
- CDC clinical overview of Long COVID
Background on Long COVID and its effects across body systems. This overview does not establish the effectiveness of TPE, EBOO or SGB for Long COVID.
How we grade evidence
Frequently asked questions
What domains does Long COVID most commonly affect?
Long COVID most commonly affects Domain 1 (brain fog, neural network function), Domain 2 (autonomic regulation and orthostatic intolerance), Domain 3 (immune function and neuroinflammation), and Domain 4 (brain energy and mitochondrial function). The mix varies between patients, which is why evaluation across all four is important before designing a recovery plan.
Is Long COVID the same as ME/CFS?
Long COVID and ME/CFS share overlapping mechanisms and symptom profiles — particularly post-exertional malaise, fatigue, and autonomic instability. Neuregen evaluates both under the same domain framework and designs programs based on the specific pattern, not the diagnostic label.
How does Neuregen approach graded return to activity for post-viral patients?
Post-exertional malaise is a real phenomenon in post-viral syndromes. We do not push activity before the autonomic and metabolic picture supports it. Graded exertional rehabilitation is introduced progressively and paced to the individual’s response, not to a generic timeline.
Is TPE appropriate for Long COVID?
TPE is labeled as emerging evidence for post-viral presentations at Neuregen — not yet a standard of care. It is considered when the inflammatory and immune picture is a dominant feature, and after more established interventions are in place.
Start with a Strategy Consultation
A real clinical conversation, not a sales call. We review your history, answer your questions, and discuss with you whether Neuregen is the right fit.
8090 N. 85th Way, Suite 100, Scottsdale, AZ 85258 · Mon–Thu, 9:00 AM – 5:30 PM