Blood Rehabilitation Therapies
Neuregen’s Blood Rehabilitation Therapies are designed for people whose brain and nervous-system recovery may be limited by persistent inflammation, immune dysregulation and other harmful circulating factors. By integrating therapeutic plasma exchange (TPE; plasmapheresis), the EBO2 protocol and brain rehabilitation, we work to improve the internal environment in which the brain is trying to heal — so rehabilitation can gain traction and you can think more clearly, function more fully and reclaim more of your life.
Explore How Blood Rehabilitation Works
Clarity and energy feel hard to hold onto. You may be dealing with fatigue, brain fog, dizziness, headaches, pain, disrupted sleep or mood changes — without a clear explanation.
Symptoms keep interrupting your progress. Immune concerns, an exposure history or recurring flares may sit alongside sensitivities, autonomic symptoms and a sense that your health keeps slipping backwards.
Brain fog. Fatigue that doesn't lift. A brain that feels like it's running on empty. Your blood carries more than nutrients. It can transport the inflammation and toxins working against your brain and nervous system. Blood rehabilitation clears that burden and gives your brain a clear foundation to work from. We rarely offer this as a standalone therapy. It's part of a holistic brain rehabilitation plan, which is something almost no one else is offering. You'll be comfortable in a recliner the whole time. We'll be checking on you throughout, and most of the time people just relax, read, or watch TV. It's a calm couple of hours, not a big ordeal. If this sounds like something your brain needs, let's talk about whether this is right for you.
These concerns can start the conversation. Your evaluation helps clarify the cause, the evidence and whether a blood-based therapy belongs in your care.
“I can’t get clear. I’m constantly fatigued, foggy and react to so many things in my environment.”
Learn more“I have unpredictable reactions — histamine issues, flares, and feel like my immune system is stuck on high alert.”
Learn more“I’m worried about what’s in my body — chemicals, heavy metals, microplastics, PFAS — and how it’s affecting my brain and health.”
Learn more“I have brain fog, headaches, dizziness and just don’t feel like myself.”
Learn more“Since a viral illness, I’ve had persistent fatigue, brain fog, sleep problems and a decline in what I can do.”
Learn more“I want to protect my brain and stay sharp. I’m concerned about memory decline and Alzheimer’s.”
Learn moreIllustrative portraits and example concerns; these are not patient testimonials or a list of proven treatment indications.
The 7 Domains of Recovery™
What it carries can influence your health.
The brain does not recover in isolation. Circulating immune and inflammatory factors can affect its function. Understanding whether those factors are contributing to your symptoms helps us decide what to address.
Neuregen’s 7 Domains of Recovery™ connects that evaluation to the rest of your health. We consider where TPE, the EBO2 protocol or photodynamic blood therapy may fit — and what rehabilitation and ongoing care should happen around it.
We assess memory, attention and cognitive function, and consider whether a diagnosed immune or inflammatory condition may be contributing to changes.
We look at dizziness, heart-rate changes and stress responses alongside immune findings, medications and other possible drivers of autonomic symptoms.
TPE can remove circulating antibodies and other plasma components. We ask whether there is a clinically meaningful target and evidence for treating the specific condition.
Fatigue and reduced stamina can have several causes. We consider sleep, nutrition, metabolic health and relevant lab findings alongside the rest of your evaluation.
Pain, balance and joint stability still need their own assessment. Movement and physical rehabilitation remain part of the plan when these factors limit function.
We track mood, sleep, coping and participation in daily life. Psychological and behavioral care can support recovery alongside treatment of physical symptoms.
We consider relevant exposures, daily demands, relationships and support. Addressing an ongoing exposure and building sustainable routines may matter as much as a procedure.
These domains describe what we assess and track. They are not a claim that each blood therapy improves every domain; evidence depends on the procedure and its specific use.
We start with your history, symptoms and goals, then select targeted baseline labs. Together, those findings help determine candidacy and guide a plan built around you.
We review your symptoms, medical history, prior testing and goals to decide whether blood rehabilitation deserves a closer look.
We select baseline labs around your history and the proposed procedure. Relevant findings help assess medical stability, possible treatment targets and whether it is safe to proceed.
We explain your results, treatment options, evidence, risks and alternatives. Together, we decide whether a blood therapy belongs alongside your rehabilitation and other care.
We follow symptoms, day-to-day function and relevant labs. Your response guides whether to continue, change or stop a treatment, and what comes next.
We move forward only when a therapy is an appropriate fit. The choice, sequence and frequency depend on your findings, the evidence, your goals and how you respond.
Talk through your optionsBlood Rehabilitation
Blood-based therapies, selected around your findings and integrated with rehabilitation to support brain and nervous-system recovery.
“Blood therapies are being increasingly adopted by cutting-edge medical and regenerative clinics. Neuregen’s approach is unique because these therapies are integrated into a broader brain, nervous system, and functional rehabilitation model.”
Blood therapies only make sense in relation to a specific clinical question. We review the indication, evidence and risks for TPE or EBOO separately, then consider whether either has a role alongside rehabilitation and your existing medical care.
Blood therapies are tools. The differentiator is the clinical reasoning system that determines which tools belong together, for which patient, in what sequence, and toward what measurable recovery goals.
Therapeutic Plasma Exchange (TPE)
Plasma carries proteins, antibodies and other circulating substances. TPE removes plasma and replaces it with selected fluid while returning your blood cells. It can help in conditions where specific plasma components contribute to illness.
Plasma is separated and removed. Your blood cells return with replacement fluid, usually albumin or donor plasma, selected for the procedure.
Extracorporeal Oxygenation
Blood passes through an external circuit for oxygen–ozone exposure before returning to the body. EBO2 is a name used for related protocols. Proposed effects on inflammation and brain function remain under investigation.
Equipment and protocol steps vary. This process differs from removing and replacing plasma in TPE.
Photodynamic Blood Therapy
HemeaLumen treats a portion of blood outside the body using controlled, multiwavelength light before returning it. The proposed biological effects and potential clinical uses require evaluation for the specific condition being treated.
The manufacturer describes a multiwavelength light system. The specific protocol and clinical evidence should be discussed separately.
The device description explains how blood is exposed to light; it does not establish that the procedure improves dementia, brain fog or other neurologic conditions.
It should not be confused with conventional extracorporeal photopheresis, which uses a light-activated drug and ultraviolet light for specific conditions. Evidence for that procedure cannot automatically be applied to HemeaLumen.
Before proceeding, we discuss the exact protocol, evidence for your condition, regulatory status, risks, alternatives and how a response would be measured.
NCI: what conventional photopheresis involvesDiagrams show the basic processes; they do not demonstrate treatment benefit or removal of every harmful substance. The evidence for each therapy depends on what it is used for; see the evidence for each use. Your evaluation determines which therapy, if any, belongs in your plan.
Evidence differs by procedure and by condition. These topics may enter an evaluation; their inclusion here does not mean a blood therapy is appropriate for every person.
Neuregen integrates AMBAR-informed plasma exchange into a comprehensive cognitive program that includes diagnostics, brain rehabilitation, metabolic support, and a caregiver pathway.
In selected patients with complex neurologic illness linked to mold or environmental exposure, TPE may be considered alongside Domain 3 (Immune & Neuroinflammatory Regulation) and Domain 7 (Environmental Context). Exposure assessment is part of the plan, not only the infusion.
Blood rehabilitation in the context of Long COVID and post-viral syndromes draws on Neuregen’s integration of Domains 1, 2, 3, and 4 — neurorehabilitation, autonomic regulation, immune biology, and metabolic support in one coordinated plan.
Mast Cell Activation Syndrome with nervous-system-dominant symptoms is a named flagship condition in Neuregen’s clinical framework. Psychiatric integration alongside blood rehabilitation is what lets the plan address the nervous-system side of MCAS, not only the immune side.
Our Commitment to Transparency
We label evidence for the specific use of a therapy. Your plan also considers safety, alternatives and your goals.
Therapeutic plasma exchange (TPE) for selected autoimmune neurologic conditions
Evidence: EstablishedFor selected autoimmune neurologic conditionsTherapeutic plasma exchange (TPE) for mild-to-moderate Alzheimer’s disease (AMBAR protocol)
Evidence: ModerateFor the studied albumin-replacement protocol in mild-to-moderate Alzheimer’s; further confirmation is needed.Therapeutic plasma exchange (TPE) for mold / environmental and CIRS-related neurologic illness
Evidence: InvestigationalEarly-stage evidence; offered with explicit informed consent and no outcome guarantee.Therapeutic plasma exchange (TPE) for long COVID and post-viral neuropsychiatric symptoms
Evidence: InvestigationalResearchers are actively investigating plasma-based approaches for complex post-infectious conditions; evidence for these applications is still emerging.Therapeutic plasma exchange (TPE) for MCAS with CNS- and psychiatric-dominant symptoms
Evidence: InvestigationalEarly-stage evidence; offered with explicit informed consent and no outcome guarantee.EBOO / EBO2 for brain and nervous-system recovery
Evidence: InvestigationalFor brain and nervous-system recoveryHemeaLumen for brain and nervous-system recovery
Evidence: InvestigationalFor brain and nervous-system recoveryEach level describes the evidence for a particular treatment and use. It does not guarantee a specific outcome or indicate FDA approval.
| Level | Label | What It Means |
|---|---|---|
| Level 1 | Strong | Multiple high-quality studies consistently support meaningful benefit for this use. |
| Level 2 | Moderate | Good clinical evidence supports benefit, but important uncertainty remains. |
| Level 3 | Emerging | Early clinical evidence suggests potential benefit, but is not yet strong or consistent. |
| Level 4 | Preliminary | Evidence is limited to small studies, observational data or indirect clinical evidence. |
| Level 5 | Investigational | There is a rationale or very early evidence, but clinical benefit has not been established. |
“Established” describes a recognized clinical use; it is not an automatic Level 1 or Level 2 rating.
Apheresis recommendations are indication-specific. An established use for one disease does not establish TPE for Alzheimer’s, Long COVID, MCAS or environmental illness.
Your plan determines the care and the fees. We explain what is included and provide a written estimate before treatment. Neuregen is an out-of-network specialty clinic.
Research & Evidence
How Neuregen labels evidence, from established to investigational, for each blood therapy indication.
Apheresis and environmental-medicine credentials behind this program
Neuregen brings the blood-therapy discussion into the same plan as neurologic, autonomic and functional care. We ask what a proposed intervention would change in daily life and how that change would be assessed.
Dr. David George: Board certifications and training in functional neurology, integrative psychiatry, and mental health; certified brain injury specialist.
Training most relevant to this area
These are the founder’s qualifications. We confirm the treating clinician and their role when discussing your plan.
See Dr. George’s full credentialsBlood Rehabilitation is Neuregen’s category name for blood-based therapies including Therapeutic Plasma Exchange (TPE), EBOO/EBO2 and HemeaLumen photodynamic blood therapy. We consider these within a broader brain, nervous-system and functional rehabilitation plan. Their mechanisms, risks and evidence differ; inclusion in the menu does not mean each is appropriate for every condition.
Blood rehabilitation may be considered for selected patients with complex neurologic, neuroimmune, or post-infectious presentations — including Alzheimer’s and cognitive decline, MCAS with CNS-dominant symptoms, Long COVID-related neuropsychiatric symptoms, and mold- or CIRS-related neurologic illness. We determine whether any blood therapy belongs in a patient’s plan after a full medical review of the diagnosis, relevant evidence, risks and alternatives.
We connect the blood-therapy evaluation to brain, nervous-system and functional rehabilitation. Your history, targeted testing and goals guide whether a procedure belongs in your care and when to use it. We track your response and coordinate rehabilitation, autonomic support, metabolic care and psychiatric care as appropriate.
Neuregen is an out-of-network specialty clinic. Patients are responsible for fees at the time of service. Specific fee information is provided in writing at the strategy consultation.
No referral is required. The starting point is a strategy consultation to determine whether Neuregen is a clinical fit for your situation — a real clinical conversation, not a sales call. If it is, we then conduct a full medical review and build a personalized plan.
Ongoing fatigue or difficulty thinking may already be limiting your work and family life. An evaluation can help organize what is known, what remains uncertain and whether further investigation is useful before considering blood therapy.
8090 N. 85th Way, Suite 100, Scottsdale, AZ 85258 · Mon–Thu, 9:00 AM – 5:30 PM