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Neuregen · Scottsdale, Arizona · 866-999-1177
Providers – Refer Your Patient

Start with what life feels like now

What should you weigh before ketamine for PTSD?

We help people with a body that stays on alert by connecting physical symptoms with their recovery needs so that they can work toward easier sleep and daily routines.

How we look at the whole picture
Illustrative portrait of a thoughtful woman beside a window.

You know you are safe, yet your heart races, your muscles tighten or a small sound puts you on edge.

It can be hard to sleep, concentrate or feel present with the people you care about.

You do not need to know which treatment to ask for. Start with what has changed and what you want to be able to do again.

The 7 Domains of Recovery™

Your symptoms may belong in the same conversation.

Stress responses, sleep, concentration and physical symptoms can overlap. The seven-domain approach considers those connections without reducing every symptom to a psychological explanation.

Neuregen's proprietary 7 Domains of Recovery framework organizes that conversation around seven connected parts of your life and health. We consider all seven, then focus the evaluation on the questions your history raises.

Explore our clinical framework
  1. 1Brain function & neural networks

    What has changed in your memory, concentration, balance or sensory tolerance?

  2. 2Autonomic & nervous system regulation

    What happens when you stand, move, rest or encounter stress?

  3. 3Immune function & neuroinflammation

    What immune history, reactions or symptoms need a closer look?

  4. 4Brain energy & metabolic health

    What affects your energy through the day and after activity?

  5. 5Structure, stability & body-to-brain signals

    How do pain, posture, movement and stability affect what you can do?

  6. 6Psychological flexibility & behavioral recovery

    How are mood, stress and patterns of coping affecting your day?

  7. 7Life, relationships & environment

    What demands, relationships and support shape your recovery?

A plan starts with the things you want to do again.

We discuss your current symptoms, what feels safe to talk about, and the support you already have. The evaluation helps us agree on priorities and a pace you can participate in.

  1. 01

    Tell us what you want your life to look like

    We start with what has changed, what you have tried, and the activities you most want to return to.

  2. 02

    Answer the questions the history leaves open

    We review prior reports and select relevant assessments. You should understand what each assessment is meant to clarify.

  3. 03

    Agree on the priorities and the first steps

    We discuss the findings, possible approaches, costs and practical constraints. The plan sets an order that fits your situation.

  4. 04

    Check what changes and adjust together

    We compare your response with the starting point, including daily function. If something is not helping, we discuss what needs to change.

Only then do we discuss which therapies, if any, belong in your plan. The choice depends on the findings, the evidence, your preferences and how you respond.

Talk through your situation

Ketamine Therapy · Indication

Ketamine for PTSD & Trauma

When a nervous system has been stuck in the same protective patterns for years, ketamine can open a window where real change becomes possible — and we make sure that window is used well.

Conceptual illustration of a delicate neural network inside a translucent shell.

Conceptual artwork for the care discussion. Individual findings and treatment options require clinical evaluation.

PTSD as a nervous-system problem

PTSD involves a nervous system that has reorganized itself around a persistent threat state. Sympathetic dominance, hypervigilance, and intrusive re-experiencing are not simply psychological — they reflect measurable changes in autonomic function, HPA axis regulation, and the fear circuitry of the brain. Treatment that addresses only the psychological layer, or only the pharmacologic layer, leaves the underlying physiology intact.

At Neuregen, ketamine for PTSD is delivered within a broader context that includes autonomic assessment and, where indicated, SGB (stellate ganglion block) — which targets the autonomic substrate of the PTSD state. The pairing is not required, but it reflects the integrated approach: address the psychology, the pharmacology, and the physiology together.

Every plan starts from the same map: the 7 Domains of Recovery.

How it fits your plan

PTSD care begins with your current symptoms, treatment history and support. Any ketamine option is discussed in that context, including its evidence, risks and alternatives.

Mood, sleep, concentration and physical symptoms can affect the same parts of your day. We consider them together before discussing a specific psychiatric approach, so psychotherapy or medication decisions fit the wider care plan.

We review your history, explain the findings, agree on next steps and check how you respond.

Potential Therapies

We use established medicine where it works, and emerging medicine where it makes sense.

These are options to discuss after evaluation, not a predetermined treatment plan. Each label refers to the condition or indication described beside that therapy; evidence can differ for another use. An evidence label does not mean FDA approval.

  • Sub-anesthetic IV ketamineEvidence: Emerging

    EMERGING for PTSD — promising controlled trial data, active investigation, not yet a standard of care for PTSD specifically.

  • The psychotherapy integration layer — particularly relevant for trauma, where the therapeutic structure around the dosing window matters for lasting change.

  • Addresses the autonomic substrate of the PTSD state; offered as a complementary intervention within the program.

  • PCL-5, PHQ-9 outcome tracking

    Validated trauma and depression symptom measures used to track response.

Where the evidence stands

Ketamine for PTSD is supported by promising controlled trial data and is an active area of clinical investigation. It is not yet a standard of care for PTSD specifically, and is offered at Neuregen as an emerging but clinically justified intervention within a structured program.

Sources and what they support

How we grade evidence

Pricing

ServicePrice
Ketamine therapy, single sessionConfirmed in writing at your Strategy Consultation
Ketamine therapy, 6-session seriesConfirmed in writing at your Strategy Consultation
Ketamine-assisted psychotherapy (KAP) sessionIncludes the psychotherapy component; priced separately from infusion-only sessionsConfirmed in writing at your Strategy Consultation
Ketamine maintenance sessionBooster sessions after a completed series, scheduled by responseConfirmed in writing at your Strategy Consultation

Ketamine therapy is typically not covered by insurance. Spravato (esketamine) is sometimes covered when prescribed under its approved indications; we will tell you which applies to you before you commit.

Financing options are reviewed at your Strategy Consultation before any plan is finalized.

The training behind this care

Neuregen combines integrative psychiatric care with nervous-system rehabilitation. Our team can discuss psychological and physical concerns in the same clinical context, while explaining the qualifications and role of each treating clinician.

Dr. David George: Board certifications and training in functional neurology, integrative psychiatry, and mental health; certified brain injury specialist.

Training most relevant to this area

  • Certified Clinical Trauma Professional (CCTP)
  • PMHNP-BC
  • Active Psychotherapist
  • Certified Hypnotherapist
  • CBT-I (Cognitive Behavioral Therapy for Insomnia) trained

These are the founder’s qualifications. We confirm the treating clinician and their role when discussing your plan.

See Dr. George’s full credentials

Frequently asked questions

Is ketamine approved for PTSD?

Racemic ketamine is not FDA-approved for PTSD; esketamine (Spravato) is approved for treatment-resistant depression and MDD with acute suicidal ideation. For PTSD specifically, ketamine is used off-label based on a growing evidence base. Neuregen labels this use EMERGING and discusses the evidence at the Strategy Consultation.

How does ketamine help with PTSD?

PTSD involves sustained alterations in the brain's threat-detection and memory-consolidation circuits. Ketamine can disrupt the neural patterns maintaining those alterations and open a neuroplastic window where new associations can form. Used within a structured clinical context, this window can support restructuring of threat-response patterns.

What is the role of SGB alongside ketamine for PTSD?

SGB (stellate ganglion block) is a separate intervention that targets the autonomic substrate of the PTSD state — the sustained sympathetic overactivity that keeps the nervous system in a defensive posture. Ketamine and SGB address different parts of the same problem; combining them within a single program is a clinical decision made after reviewing the patient's full autonomic and psychiatric picture.

How long before I see results with ketamine for PTSD?

Response timelines vary by patient and are not guaranteed. Some patients notice change within the first infusion course; others do not. Neuregen uses validated outcome measures (PCL-5, PHQ-9) to track response objectively and adjusts the plan based on what the data shows.

Start with a Strategy Consultation

When distress or poor sleep keeps affecting relationships and everyday responsibilities, putting off a conversation leaves those concerns unresolved. You can ask about next steps without committing to medication or a procedure.

8090 N. 85th Way, Suite 100, Scottsdale, AZ 85258 · Mon–Thu, 9:00 AM – 5:30 PM