Start with what life feels like now

How does imaging guide an injection decision?

We help people with pain that limits sitting, walking or sleeping by examining movement and nervous-system factors so that they can work toward the activities pain has interrupted.

How we look at the whole picture

You plan your day around how long you can sit, stand or walk before pain takes over.

You have tried to keep going, but a sore neck, back or joint keeps bringing you back to the same limits.

You do not need to know which treatment to ask for. Start with what has changed and what you want to be able to do again.

The 7 Domains of Recovery™

Your symptoms may belong in the same conversation.

Pain can involve tissue, movement, nerve sensitivity, sleep and stress. The seven-domain approach considers how these factors may be sustaining the problem.

Neuregen's proprietary 7 Domains of Recovery framework organizes that conversation around seven connected parts of your life and health. We consider all seven, then focus the evaluation on the questions your history raises.

Explore our clinical framework

1Brain function & neural networks
What has changed in your memory, concentration, balance or sensory tolerance?
2Autonomic & nervous system regulation
What happens when you stand, move, rest or encounter stress?
3Immune function & neuroinflammation
What immune history, reactions or symptoms need a closer look?
4Brain energy & metabolic health
What affects your energy through the day and after activity?
5Structure, stability & body-to-brain signals
How do pain, posture, movement and stability affect what you can do?
6Psychological flexibility & behavioral recovery
How are mood, stress and patterns of coping affecting your day?
7Life, relationships & environment
What demands, relationships and support shape your recovery?

A plan starts with the things you want to do again.

We review the pattern of pain, the examination and any relevant prior imaging. We agree on a functional goal, such as sitting through a meal or walking farther, before choosing care.

01
Tell us what you want your life to look like
We start with what has changed, what you have tried, and the activities you most want to return to.
02
Answer the questions the history leaves open
We review prior reports and select relevant assessments. You should understand what each assessment is meant to clarify.
03
Agree on the priorities and the first steps
We discuss the findings, possible approaches, costs and practical constraints. The plan sets an order that fits your situation.
04
Check what changes and adjust together
We compare your response with the starting point, including daily function. If something is not helping, we discuss what needs to change.

Only then do we discuss which therapies, if any, belong in your plan. The choice depends on the findings, the evidence, your preferences and how you respond.

Talk through your situation

Precision Injection Therapies · Method

Image-Guided Injections

Every injection at Neuregen is placed under real-time imaging, so the needle reaches the target and nothing else.

Clinically: The shared method behind the Precision Injection Therapies hub: real-time ultrasound guidance for sympathetic blocks, peripheral nerve blocks, hydrodissection, and the regenerative injections offered in the Regenerative Therapies hub.

Book a Strategy Consultation How we build your plan

Conceptual artwork for the care discussion. Individual findings and treatment options require clinical evaluation.

What image guidance changes about an injection

The structures that injections target in the neck and around the skull base are small and sit next to structures that must be avoided: the vertebral and carotid arteries beside the stellate ganglion, the occipital artery beside the greater occipital nerve, the pleura below the lower cervical roots. Landmark-based injection relies on average anatomy. Ultrasound shows the actual anatomy of the person on the table, including the variations that averages hide.

With the transducer on the skin, the target nerve or ganglion, the vessels around it, and the needle tip are visible on screen at the same time. The needle is advanced along a planned path, and the injectate can be seen spreading in the intended tissue plane. If it spreads in the wrong plane, the needle is repositioned before more is given. That visual confirmation is what makes the dose reliable and the procedure repeatable.

Neuregen uses image guidance for stellate ganglion block, greater occipital nerve block, cervical hydrodissection, and the platelet-rich plasma and neural prolotherapy injections in the Regenerative Therapies hub. Epidural steroid injections, spinal facet or medial branch procedures, and radiofrequency ablation are not part of the practice; patients whose assessment points to those procedures are referred to interventional pain colleagues.

Domains most involved:

Every plan starts from the same map: the 7 Domains of Recovery.

How it fits your plan

Imaging helps guide a procedure when one is appropriate. The assessment comes first and may lead to a plan that does not include an injection.

An injection is worth discussing only when the evaluation identifies a problem it may address. We consider that problem alongside sleep, movement, autonomic symptoms and daily function, then explain what rehabilitation would involve with or without the procedure.

We review your history, explain the findings, agree on next steps and check how you respond.

Potential Therapies

We use established medicine where it works, and emerging medicine where it makes sense.

These are options to discuss after evaluation, not a predetermined treatment plan. Each label refers to the condition or indication described beside that therapy; evidence can differ for another use. An evidence label does not mean FDA approval.

Before considering experimental therapies

Stem-cell and exosome treatments discussed here for brain and nervous-system recovery are experimental, not FDA-approved treatments for these conditions. Potential benefits remain uncertain, and serious harms can occur. Their inclusion here does not establish availability or eligibility.

Peptide protocols discussed for neural repair are investigational. Compounded drugs are not FDA approved; FDA does not review their safety, effectiveness or quality before marketing. Approval and lawful use depend on the specific product and indication. Informed consent alone does not establish regulatory authorization.

We discuss the evidence, product-specific risks, alternatives and regulatory status before any treatment decision. PRP and other biologics also need a separate review for the proposed use.

FDA: regenerative medicine information FDA: compounded medicines

Stellate Ganglion Block (SGB)Evidence: Established
Established for selected sympathetically mediated pain; emerging for PTSD and preliminary for dysautonomia.
Greater Occipital Nerve BlockEvidence: Established
Occipital neuralgia, cervicogenic headache, migraine.
Cervical hydrodissectionEvidence: Emerging
Perineural fluid release of entrapped cervical and occipital nerves.
Regenerative injections (PRP, neural prolotherapy)Evidence: Emerging
Offered in the Regenerative Therapies hub under the same guidance method.

Peripheral Nerve Hydrodissection

Hydrodissection uses ultrasound-guided fluid placement to separate a peripheral nerve from adjacent tissue. The intended target is a specific site of nerve entrapment, such as the median nerve at the wrist or the ulnar nerve at the elbow.

History, examination and relevant imaging or nerve testing help distinguish an entrapment from other causes of numbness, weakness or pain. The nerve, fluid and technique all matter: carpal tunnel research cannot be assumed to apply to the tarsal tunnel or to cervical nerves.

If the findings support this approach, we explain the proposed procedure, alternatives and risks, including bleeding, infection, temporary discomfort and nerve injury. It can be paired with activity modification and rehabilitation; more severe or progressive nerve problems may need a different approach or specialist referral.

Evidence depends on the nerve, solution and technique. Carpal tunnel and ulnar-nerve trials include perineural dextrose; they do not isolate a mechanical effect or establish benefit at every entrapment site. Tarsal tunnel evidence is limited.

Compare the precision injection menu

Where the evidence stands

Ultrasound guidance for peripheral nerve and sympathetic blocks is an established practice in regional anesthesia, with evidence for improved accuracy and fewer vascular punctures compared with landmark technique. The emerging label on this page reflects the indications the injections are applied to at Neuregen, not the guidance method itself.

How we grade evidence

How we label evidence

Each grade describes the evidence for a particular treatment and use. It does not guarantee an outcome or establish regulatory approval.

Level 1
Evidence: Strong
Multiple high-quality studies consistently support meaningful benefit for this use. Results are unlikely to change substantially with additional research.
Level 2
Evidence: Moderate
Good clinical evidence supports benefit, but important uncertainty remains about magnitude, patient selection, long-term outcomes, or generalizability.
Level 3
Evidence: Emerging
Early clinical studies suggest potential benefit, but the evidence is not yet strong or consistent enough for confident conclusions.
Level 4
Evidence: Preliminary
Evidence is limited to small studies, case series, retrospective data, or indirect clinical evidence. Benefit remains uncertain.
Level 5
Evidence: Investigational
There is biological rationale or very early clinical evidence, but efficacy for this use has not been established.

Some care pages also use Established to describe an established clinical use. That label is not an automatic Level 1 or Level 2 rating; the strength of evidence must be reviewed for the specific indication.

Promising does not mean proven. Your clinician considers the indication, alternatives, risks and your circumstances before recommending care.

Pricing

Service	Price
Strategy ConsultationA real clinical conversation, not a sales call	Confirmed in writing at your Strategy Consultation

Neuregen is an out-of-network specialty clinic. Most therapies listed here are not covered by insurance; we provide itemized documentation you can submit to your insurer, and we tell you before any therapy which parts, if any, are typically reimbursed.

Financing options are reviewed at your Strategy Consultation before any plan is finalized.

The training behind this care

At Neuregen, the injection discussion sits inside a rehabilitation plan. Our team connects the proposed procedure to findings, practical goals and follow-up instead of treating the procedure as the whole course of care.

Dr. David George: Board certifications and training in functional neurology, integrative psychiatry, and mental health; certified brain injury specialist.

Training most relevant to this area

Ultrasound-guided neural hydrodissection and neural prolotherapy (perineural injection therapy)

These are the founder’s qualifications. We confirm the treating clinician and their role when discussing your plan.

See Dr. George’s full credentials

modality

condition

domain

Domain 5: Structure & Stability

trust

Safety & Standards

Frequently asked questions

What does "image-guided" mean?

The needle is placed while the target and the surrounding anatomy are visible on an ultrasound screen. The clinician watches the needle tip advance and watches the injected fluid spread, and adjusts if either is not where it should be. Landmark-based injection, by contrast, relies on surface anatomy and feel.

Does Neuregen use fluoroscopy (X-ray guidance)?

Neuregen's injections are ultrasound-guided. Ultrasound shows soft tissue, nerves, and vessels in real time without radiation, which suits the neck and skull-base targets in this hub. Procedures that require fluoroscopy, such as spinal facet injections or radiofrequency ablation, are not performed here and are referred out.

Is image guidance safer?

Seeing the vessels and the needle at the same time reduces the chance of injecting into or near a blood vessel, and confirms that the medication reaches the intended plane. Every injection still carries risk, and we review the specific risks of each procedure with you before consent.

Which injections are not offered?

Epidural steroid injections, facet and medial branch blocks, radiofrequency ablation, and other fluoroscopy-based spinal procedures. If your assessment points to one of those, Neuregen refers you to an interventional pain specialist and coordinates the rest of the plan around that care.

Start with a Strategy Consultation

If symptoms keep interrupting work, sleep or movement, that disruption is already part of your day. A consultation can help clarify the next question to investigate; it does not commit you to an injection.

Book a Strategy Consultation 866-999-1177

8090 N. 85th Way, Suite 100, Scottsdale, AZ 85258 · Mon–Thu, 9:00 AM – 5:30 PM